Active: Testosterone Enanthate
”Testosterone Enantate is an ester of the naturally occurring androgen, testosterone. It is responsible for the normal development of the male sex characteristics. In the event of insufficient testosterone production an almost complete balance of the functional, anatomic, and psychic deﬁciency symptoms can be achieved by substituting testosterone.” (Excerpt from the package insert of the German pharmaceutical group, J enapharm GmbH for its compound Testosteron-Depot.)
These lines clearly describe what an important and effective hormone testosterone is. One of the many testosterone substances is the testosterone enanthate. In a man it is normally used to treat hypogonadism resulting from androgen deficiency (1) and anemia (2). Surprisingly, in medical schools testosterone enanthate is also used in women and children. Boys and male youth take it as growth therapy (package insert, Testosteron-Depot, Jenapharm GmbH) and women take it as an ”additive treatment for certain growth forms of the nipples during post-menopause” (package insert, Testoviron-Depot—250 Schering AG).
In bodybuilding, however, it is the ”mass-building steroid.” No matter what you think of Dianabol, Parabolan, Anadrol 50, Finaject, and others, when it comes to strength, muscle mass, and rapid weight gains, testosterone is still the “King of the Road.” Testosterone Enanthate is the European counterpart to Testosterone cypionate which is predominantly available in the U.S. (see also Testosterone Cypionate). Testosterone Enanthate, as most trade names already suggest, is a long-acting depot steroid. Depending on the metabolism and the body ’s initial hormone level it has a duration of effect of two to three weeks so that theoretically very long intervals between injections are possible. Although Testosterone Enanthate is effective for several weeks, it is injected at least once a week in bodybuilding, powerlifting, and weightlifting. This, by all means, makes means since Testosterone enanthate has a plasma half-life time in the blood of only one week (Doping-verbotene Arzneimittel im Sport, Dirk Clasing and Manfred Donike, p. 66.)
The decisive advantage of Testosterone Enanthate, however, is that this substance has a very strong androgenic effect and is coupled with an intense anabolic component. This allows almost everyone, within a short time, to build up a lot of strength and mass. The rapid and strong weight gain is combined with distinct water retention since a retention of electrolytes and water occurs. A pleasant effect is that the enormous strength gain goes hand in hand with the water retention. Weightlifters and powerlifters, especially in the higher weight classes, appreciate this characteristic. In this group, Testosterone enanthate, Testosterone cypionate, and Sustanon (see also Sustanon) are the number one steroids; this is also clearly reﬂected in the dosages. Dosages of 500 mg, 1000 mg or even 2000mg per day are no rarity, mind you, per day, not per week. Sports disciplines requiring a high degree of raw power, aggressiveness, and stamina offer an excellent application for Depot-Testosterone.
Muscle Mag International, July I992., page 71: ”Pro football players are total androgen heads. Powerlifters take much heavier stacks. Professional wrestlers never come off the stuff. They have testicles the size of raisins.” Daniel Duchaine, Underground Steroid Handbook 2: ”…it is not uncommon to see very high doses in the 2000 mg-4000 mg/week range used. Most powerlifters and football players are using these megadoses.” The distinct water retention has also other advantages. Those who have problems with their joints, shoulder cartilages or whose intervertebral disks, due to years of heavy training, show the first signs of wear, can get temporary relief by taking testosterone.
For the bodybuilder, the water retention that goes hand in hand with Testosterone Enanthate cuts both ways. Certainly, one gets rapidly massive and strong; however, one’s reﬂected image after a few weeks often shows completely ﬂat, watery, and puffy muscles. The muscles appear as if they have been pumped up with air to new dimensions, yet during ﬂexing nothing happens. Those who do not believe this should bother to go visit the so-called ”bodybuilding champions” during the off-season when these exaggerated quantities of ”test” come in. A look at the now defunct bodybuilding magazine WBF makes it even clearer.
An additional problem when taking Testosterone Enanthate is that the conversion rate to estrogen is very high. This, on one hand, leads the body to store more fat; on the other hand, feminization symptoms (gynecomastia) are not unusual. However, it must be clearly stated that this depends on the athlete’s predisposition. By all means, there are athletes who even with 1000 mg +/week do not show feminization symptoms or fat deposits and who suffer very low water retention. Others, however, develop pain in their nipples by simply looking at a Testoviron-Depot ampule. Yet the additional intake of Nolvadex and Proviron should be considered at a dosage level of 500 mg+/week.
As already mentioned, Test is effective for everyone, whether a beginner or Mr. Olympia. Testosterone Enanthate also strongly promotes the regeneration process. This leads to distinctly shorter overcompensation phases, an increased feeling of well-being, and a distinct energy increase. This is also the reason why several athletes are able to work out twice daily for several hours six times a week and continue to build up mass and strength. Those who can work out again two hours after a hard leg workout know that Test works. Athletes who take Testosterone enanthate report an excessively strong pump effect during training. This ”steroid pump” is attributed to an increased blood volume with a higher oxygen supply and a higher quantity of red blood cells.
Those who take megadoses of Testosterone Enanthate will already feel an enormous pump in their upper thighs and calves when climbing stairs. Despite this we recommend that steroid novices stay away from all testosterone compounds. To make it very clear: Those who have never taken steroids do not yet need any testosterone and should wait until later when the ”weaker” steroids begin to have little effect. For the more advanced, Testosterone Enanthate can either be taken alone or in combination with other compounds.
For adding mass Testosterone Enanthate combines very well with Anadrol 50, Dianabol, Deca, and Parabolan. As an example, a stack of 100 mg Anadrol 50/day, 200 mg Deca day and 500 mg Testosterone enanthate/week works well. After six weeks of intake the Anadrol 50, for example, could be replaced by 40mg Dianabol/day. Principally, Testosterone Enanthate can be combined with any steroid in order to gain mass. Apparently a synergetic effect between the androgen, Testosterone enanthate, and the anabolic steroids occurs which results in their bonding with several receptors. Those who draw too much water with Testosterone Enanthate and Dianabol or Anadrol, or who are more interested in strength without gaining 20 pounds of body weight should take Testosterone Enanthate together with Oxandrolone or Winstrol. The generally taken dose, as already mentioned, varies from 250 mg/week up to 2000 mg/day. In our opinion the most sensible dosage for most athletes is between 250-1000 mg/ week. Normally a higher dosage should not be necessary. When taking up to 500 mg/week the dosage is normally taken all at once. A higher dosage should be divided into two injections per week. The quantity of the dose should be determined by the athlete’s developmental stage, his goals, and the quantity of his previous steroid intake. The so called beach-and-disco bodybuilders do not need 1000 mg of Testosterone enanthate/week. Our experience is that the Testosterone enanthate dosage for many, above all, depends on their financial resources. Since it is not, by any means, the most economic testosterone, most athletes do not take too much.
Testosterone Enanthate has a strong influence on the hypothalamohypophysial testicular axis. The hypophysis is inhibited by a positive feedback. This leads to a negative inﬂuence on the endogenic testosterone production. Possible side effects are described by the German Jenapharm GmbH in their package insert for the compound Testosteron Depot: ” In a high-dosed treatment with testosterone compounds an often reversible interruption or reduction of the spermatogenesis in the testes is to be expected and consequently also a reduction of the testes size.” Schering AG, the manufacturer of Testoviron-Depot250, also suggests the same idea in its package insert: ’A long-term and high-dosed application of Testoviron Depot250 will lead to a reversible interruption or reduction of the sperm count in the testes, thus a reduction of the testes size must be expected.” Consequently, after reading these statements, additional intake of HCG should be considered. Those who take Testosterone Enanthate should consider the intake of HCG every 6-8 weeks. An injection of 5000 I.U. every fifth day over a period of 10 days (a total of 3 injections) helps to reduce this problem.
At the end of the testosterone treatment the administration of HCG, Clomid, Nolvadex and Clenbuterol is now quite common. To some extent the use of these compounds helps absorb the catabolic phase and helps elevate the endogenic testosterone level. By this method the strength and mass loss which occur in any event can be reduced.
Those who go off Testosterone Enanthate cold-turkey, after several weeks of use will wonder how rapidly their body weights and former voluminous muscles will decrease. Even a slow tapering-off phase, that is reducing the dosage step by step, will not prevent a noticeable reduction. The only options available to the athlete consist of taking testosterone-stimulating compounds (HCG, Clomid, Cyclofenil), anti-catabolic substances (Clenbuterol, Ephedrine), or the very expensive growth hormones, or of switching to milder steroids (Deca, Winstrol, Primobolan).
Most can get massive and strong with Testosterone Enanthate. However, only very few are able to retain their size after discontinuing the compound. This is also one of the reasons why really good bodybuilders, powerlifters, weight-lifters, and others take it all year long.
The side effects of Testosterone Enanthate are mostly the distinct androgenic effect and the increased water retention. This is usually the reason for the frequent occurrence of hypertony. Those who have a predisposition for high blood pressure or whose blood pressure is elevated when they begin taking Testosterone Enanthate should have it periodically checked by a physician. If necessary the intake of an antihypertensive drug such as Catapresan is advisable.
Many athletes experience a strong acne vulgaris with Testosterone Enanthate which manifests itself on the back, chest, “shoulders, and arms more than on the face. Athletes who take large quantities of test can often be easily recognized because of these characteristics. It is interesting to note that in some athletes these characteristics only occur after use of the compound has been discontinued, which implies a rebound effect. In severe cases the medicine Accutane can help. The already discussed feminization symptoms, especially gynecomastia, require the intake of an anti-estrogen. Sexual overstimulation with frequent erections at the beginning of intake is normal. In young athletes, ”in addition to virilization,testosterone can also lead to an accelerated growth and bone maturation, to a premature epiphysial closing of the growth plates and thus a lower height” (Jenapharm GmbH, package insert for Testosteron—Depot).
Since mostly taller athletes are successful in bodybuilding, young adults should reﬂect carefully before taking any anabolic/androgenic steroids, in particular, testosterone.
Other possible side effects are testicular atrophy, reduced spermatogenesis, and especially an increased aggressiveness. Those who transfer this aggressiveness to their training and not their environment do not have to worry. Unfortunately this is not the case in some athletes who take Testosterone Enanthate. Testosterones are primary reasons for some eruptions. In particular, high doses are in part responsible for anti-social behavior among its users. One can talk here of a sort of ”superman syndrome” that occurs in some users. Daniel Duchaine discusses this problem in his book Underground Steroid Handbook 2 : ”Men, though, with increased aggressiveness can become outright frightening and dangerous, as well as being general dickheads. Try riding in a car with a 300 pound, acne ridden, hungry testosterone respository during rush hour traffic.”
Although Testosterone Enanthate is broken down through the liver, this compound is only slightly toxic when taken in a reasonable dose; therefore, changes of the liver values do not occur as often as with the oral 17-alpha alkylated steroids. Very interesting information as to the liver intoxication of testosterone can be found in the book Doping by Dirk Clasing written in collaboration with Manfred Donike et al. On page 60 one reads: “After earlier exams (Kriiskemper 1975) guidelines for the evaluation of possible liver intoxication by steroids can be made (tab. 3). According to these guidelines, testosterone and its esters seem to be non-toxic or very slightly toxic to the liver. This is clinically confirmed: even in cases with considerable pre-existing damage to the liver (alcoholic cirrhosis), testosterone was administered without additional liver damage.” (Gluud 1988; Kley 1982).
Further potential side effects can be deep voice and accelerated hair loss. ”Some steroid can make your hair fall out. It is rarely an anabolic steroid that does this, but rather the androgens, notably the testosterones.” (Daniel Duchaine, Underground Steroid Handbook 2, page 61.)
Women should normally avoid its intake since it could result in unpleasant androgen-linked side effects. Jenapharm GmbH describes these possible side effects of Testosterone Enanthate in its package insert for the compound Testosteron-Depot: “The use of testosterone in women may cause symptoms of virilization such as acne vulgaris, hirsutism, androgenetic alopecia, voice changes, and occasional clitorial hypertrophy and an unnaturally perceived increase in libido. Changes in voice and alopecia must be classified as irreversible, hirsutism and clitorial-hypertropy as in part reversible.” Women who are not afraid of this are found at many competition scenes. In our opinion, 250mg is the maximum quantity of Testosterone enanthate that a female athlete should take each 7-10 days. However in competition bodybuilding and especially in powerlifting much higher dosages and shorter injection intervals have been observed in women.
Another interesting side effect of Testosterone enanthate is mentioned in the bodybuilding magazine Muscle Media 2000, June-July 1993 on page 45. Judging whether this is positive or negative is left to the reader. ‘A few years ago, the Lancet Medical Journal of England reported that they found testosterone (the prototype anabolic steroid) to be a remarkably effective form of male birth control. Researchers conducted a 12 month study which included 270 men and determined that weekly injections of the hormone testosterone were ’safe, stable, and effective.’ They discovered that weekly testosterone injections had a success rate of 99.2% as a birth control method. That makes it more effective than the birth control pill (97%) and much more effective than condoms (88%). The study also revealed that the effects of the contraceptive injections were entirely reversible upon discontinuing administration of the drug and that the testosterone injections produced minimal side effects.”
These results stress at least the need for testosterone-stimulating compounds during and after the intake of Testosterone Enanthate. Since it is effective for such a long period of time, Testosterone Enanthate is always taken more frequently by athletes during their ”steroid intervals.” An injection of 250 mg every 2-3 weeks helps maintain strength and mass. Whether this application makes sense remains to be seen; the fact is that it works.
Looking toward competitions with doping tests Testosterone Enanthate is also an interesting substance. Since exogenous testosterone can only be detected through the testosterone/epitestosterone values, it is important not to exceed the critical 6:1 ratio. Daniel Duchaine, Ask the Guru: ”Experimental military trials have shown that up to 300 mg a week of Testosterone Cypionate or Enanthate can be used while still maintaining the six to one ratio.” However, we do not give any guarantee for the practical use of this information. The over bridging doping of the former GDR athletes with Testosterone enanthate and propionate worked perfectly. The athlete can find more on this subject in the book Doping by Brigitte Berendonk. So far it is published only in German.