Searle Company introduced the substance oxandrolone to the U.S. market in 1964 under the name Anavar. It enjoyed great popularity for over two decades until, on July 1, 1989. When they phased out production of Anavar. Today Anavar is manufactured under its various generic names in only a few countries.
Relatively weak steroid
Anavar is a weak steroid with only a slight androgenic component. They have shown that Anavar, when taken in reasonable dosages, rarely has side effects. They developed Anavar for women and children.
Anavar is one of the few steroids which does not cause an early stunting of growth in children. It does not prematurely close the epiphyseal growth plates. Oxandrolone therefore used in children to stimulate growth, and in women to prevent osteoporosis. Oxandrolone causes very light virilization symptoms, if at all. This characteristic makes Oxandrolone a favored remedy for female athletes. Observing a daily dose of 10-15mg, masculinizing symptoms occurs only rarely.
Bodybuilders and powerlifters love Oxandrolone
Bodybuilders and powerlifters, in particular, like Anavar for three reasons. First, Anavar causes strength gain by stimulating the phosphocreatine synthesis in the muscle cell. Without depositing liquid (water) in the joints and the muscles.
Powerlifters and weightlifters who do not want to end up in a higher weight class. Oxandrolone allows them to get stronger without gaining body weight. The combination of Anavar and 2.0-30 mg Halotestin daily has proven to be very effective. The muscles also look harder. Similarly good results can be achieved by a simultaneous intake of Anavar and 120-140 mcg Clenbuterol per day.
Although Oxandrolone itself does not cause a noticeable muscle growth it can clearly improve the muscle-developing effect of many steroids. Deca, Dianabol, and the various testosterone compounds, in particular, combine well with Oxandrolone to achieve a ”mass buildup” because the strength gain caused by the intake of these highly tissue-developing and liquid-retaining sub-stances results in an additional muscle mass. A stack of 200 mg Deca/week, 500 mg Testosterone enanthate (e.g.Test Enanthate)/week, and 25mg Oxandrolone/day leads to a good gain in strength and mass in most athletes. Deca has a distinct anabolic effect and stimulates the synthesis of protein; Oxandrolone improves the strength by a higher phosphocreatine synthesis; and Testosterone enanthate increases the aggressiveness for the workout and accelerates regeneration.
No conversion to estrogen
The second reason why Anavar is so popular is that this compound does not aromatize in any dosage. The body converts a part of the testosterone present into estrogen. This aromatization process, depending on the predisposition, can vary distinctly from one athlete to another. Anavar is one of the few steroids which cannot aromatize to estrogen. This characteristic has various advantages for the athlete.
With Oxandrolone the muscle system does not get the typical watery appearance as with many steroids, thus making it very interesting during the preparation for a competition. In this phase it is especially important to keep the estrogen level as low as possible since estrogen programs the body to store water even if the diet is calorie-reduced. In combination with a diet, Oxandrolone helps to make the muscles hard and ripped. Although Oxandrolone itself does not break down fat, it plays an indirect role in this process because the substance often suppresses the athlete’s appetite.
Anavar can cause bloating in some athletes. In several athletes this results in nausea and vomiting when the tablets are taken with meals. The package insert of the Italian Oxandrolone notes its effect on the activity of the gastrointestinal tract. Some athletes thus report continued diarrhea. Although these symptoms are not very pleasant they still help the athlete break down fat and become harder.
Those who work out for a competition or are interested in gaining quality muscles should combine Oxandrolone with steroids such as Winstrol, Tren100, Masteron, Tren200, and Testosterone propionate. A stack of 50mg Winstrol every two days, 50mg Testosterone Propionate every two days, and 2.5 mg Oxandrolone every day has proven effective. Another advantage of Oxandrolone’s non-aromatization is that athletes who suffer from high blood pressure or develop gynecomastia of the thymus glands when taking stronger androgenic steroids will not have these side effects with this compound. The Oxandrolone/Deca100 stack is a welcome alternative for this group of athletes or for athletes showing signs of poor health during mass buildup with testosterone, Dianabol, or Anadrol 50. Athletes over forty should predominantly use Oxandrolone.
Effects on hormone production
The third reason Oxandrolone is popularity. It does not suppress the body’s own hormone production. Even at very high dosages. No negative feedback takes place between the hypothalamo hypophyseal-testicular axis. During Oxandrolone intake the testes signal the hypothalamus not to reduce or to stop the release of GnRH (gonadotropin releasing hormone) and LHRH (luteinizing hormone releasing hormone). Oxandrolone does not convert into estrogen.
Dr. Mauro G. Di Pasquale writes on page 23 of his book Anabolic Steroid Side Effects – Facts, Fiction and Treatment: “It is also thought that estrogens, produced from the aromatization of testosterone and other anabolic steroids in parts of the brain and hypothalamus, inhibit LH secretion, and thus decrease testosterone production.” The American physician, Dr. Rober Kerr, confirmed this thesis in his book The Practical Use of anabolic Steroids with Athletes, where on page 23 he states: “Oxandrolone (Anavar), when given to normal men in high doses does not reduce the seminal volume or count, nor can it be converted (aromatized) into estrogen, Goodman and Gilman have thus concluded that perhaps the feedback mechanism is not activated by the amount of testosterone as much as the estrogen level.”
For this reason Oxandrolone combines very well with Androxon, since Androxon does not aromatize in a dosage of up to 240 mg daily and has only slight influence on the hormone production. The daily intake of 280 mg Androxon and 25 mg Oxandrolone results in a good gain in strength. In steroid novices also gain muscle mass without excessive water retention.
As for the dosage of Oxandrolone, 8-12 tablets in men and 5-6 tablets in women seems to bring the best results. The rule of thumb to take 0.125mg/pound of body weight daily has proven successful in clinical tests. Taking the tablets two to three times daily after meals thus assuring an optimal absorption of the substance. Those who get the already discussed gastrointestinal pain when taking Oxandrolone are better off taking the tablets one to two hours after a meal or switching to another compound.
Oxandrolone is only slightly toxic and has few side effects. Several athletes use it over long periods of time. You should not take for several consecutive months. As with almost all oral steroids it is 17-alpha alkylated and can become liver toxic. Oxandrolone is an all-purpose remedy which, depending on the athlete’s goal, is very versatile.
Women who react sensitively to the intake of anabolic steroids achieve good results when combining Oxandrolone/Primabolan Tabs and/ or Clenbuterol, without suffering from the usual virilization symptoms. Women, however, should not take more than 6 tablets daily. Otherwise, androgenic-caused side effects such as acne, deep voice, clitorial hypertrophy or increased growth of body hair can occur.
Probably the largest disadvantages that comes along with Oxandrolone are its high price.