Clomid. Active: Clomiphene Citrate

Clomiphene Citrate is not an anabolic/androgenic steroid. Since it is a synthetic estrogen it belongs, however, to the group of sex hormones. In school medicine, they normally use clomiphene to trigger ovulation. Those who cannot make much of this should read the package insert of Merrell Dow Pharma GmbH Company enclosed with the compound. Under ”application” one reads the following: ”To trigger the release of an ovum (ovulation) in women who want children and have certain ovary malfunctions…” Some might ask now what such a compound is doing in the drug arsenal of athletes. Those who know the effect of Clomid will immediately understand why its use by numerous athletes.

Stimulates the release of gonadotropin

By setting in motion the process of releasing hormones stimulates the release of gonadotropin and triggers ovulation in women with anovulatory cycles and who are sterile because of this. They make this drug for women but it influences men. The manufacturer of Dyneric, the Merrell Dow Pharma GmbH, writes in its package insert for the German version of Clomid. ”Dyneric causes an improved activity between midbrain, pituitary gland, and ovaries.” They do not mention is that Dyneric also improves the activity between midbrain (hypothalamus), pituitary gland (hypophysis), and testes in men. It has a strong influence on the hypothalamo hypophyseal testicular axis. It stimulates the hypophysis to release more gonadotropin so that a faster and higher release of FSH (follicle-stimulating hormone) and LH (luteinizing hormone) occurs. This results in an elevated endogenous (body’s own) testosterone level.

When using anabolic/androgenic steroids, the body reduces testosterone production. Clomiphene Citrate counters this effect. In most cases, Clomiphene Citrate can normalize the testosterone level and the spermatogenesis (sperm development) within 10-14 days. Athletes take Clomiphene Citrate after they discontinue steroids. It is extremely important to quickly bring the testosterone production to normal levels, so it minimizes the loss of strength and muscle.

Clomid and HCG

Even better results can be achieved if Clomid is combined with HCG or when Clomiphene Citrate is used after the intake of HCG. The difference between Clomid and HCG lies in the fact that Clomiphene Citrate has a direct influence on the hypothalamus and the hypophysis, thus regenerating the entire regulating cycle while HCG imitates the effect of the luteinizing hormone (LH) which stimulates the Ledig’s cells to produce more testosterone. Since HCG, unlike Clomid, leads to a distinctly elevated plasma-testosterone level within a few hours, many athletes first take HCG and then Clomid (see also HCG).

Paradoxically, although Clomid is a synthetic estrogen it also works as an anti-estrogen. The reason is that Clomid has only a very low estrogenic effect and thus the stronger estrogens which, for example, which forms during the aromatization of steroids, are blocked at the receptors. These would include those that develop during the aromatizing of steroids. This does not prevent steroids from aromatizing. However, increased estrogen cannot attach to the receptors and mostly deactivated. Water retention and possible signs of feminization reduce or completely avoided.

Side Effects

Since the anti-estrogenic effect of Clomid is lower than those found in Proviron and Nolvadex, it is mainly taken as a testosterone stimulant. Side effects of Clomid are very rare if reasonable dosages are taken. Possible side effects are climacteric hot flashes and occasional visual disturbances which can manifest themselves in blurred vision, giving flickering or flashing. Should visual disturbances occur, the manufacturer recommends discontinuing Clomid treatment. Inadequate liver functions cannot be excluded but are very unlikely. In women enlargement of the ovaries and abdominal pain can occur since Clomid stimulates the ovaries. When taking Clomid multiple pregnancies are possible as well. As for the dosage, 50-100mg/day (1-2 tablets) seems to be sufficient. The athletes do not usually take it for a prolonged time. It must exclude its application as an anti-estrogen. For that purpose, it would have to be taken for several weeks.

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