IFG-1 Reserach article

I received this mail I found interesting so I added it to the site for everybody to broaden their knowledge:

I have been seriously considering the use of HGH (specifically igf1) after 3
days of searching (very well hidden I must say) I came to the conclusion
that there might be some dangers in using this substance HYPERLINK
"http://www.cancerindex.org/geneweb/IGF1.htm"
http://www.cancerindex.org/geneweb/IGF1.htm and HYPERLINK
"http://www.thehormoneshop.com/prostate.htm"
http://www.thehormoneshop.com/prostate.htm you have a look there. I don’t
know if you would find this in your interest to add some of this to your
site.


My thoughts:I have read some of the studies you suggested and I find it quote interesting. By-enlarge there seems to be very little correlation between cancer and IGF-1. One has to bear in mind that these studies focused on the serum IGF-1 levels and this is quite different from what the levels would be in the case of taking IGF-1. IGF-1 was never produced by any manufacturers so it is not available for clinical use. Some studies even point to a reduction in cancer risk.

An important factor to consider is that do a degree there as been a long term study on the effects of GH and IGF-1 by definition refereeing to the combined use of Insulin and GH) similar to the longest running informal clinical, human-based study known as bodybuilding. In this informal but highly informative trial we see that there are some definite correlation between certain conditions and the use of Anabolic steroids, there can be further broken down into Long term use and cross-correlated with very high dosage use.
The fact that some individuals are in fact alive seems to contradict 100% of the medical opinions or prediction on the use of Anabolic steroids. The case is further aggravated in that some of these individuals are ridiculously fit and strong, quite the opposite of what the medical experts would predict.

Some problem most definitely exist in some of these heavy users, from prostate cancer, but considering that we know they are also heavy GH and Insulin users and in many cases drug users as well, they certainly pose the "worst case scenario" group if there ever was one. In tracking the deaths that have occurred in the last 10 year within the sport some interesting information and patterns come to light.

The reasons for death typically follow the same pattern, first steroids are blamed, (in more general sports like athletics, the latest performance enhancing drug is blamed in an attempt to scare people off using it), then the issues surrounding other substance abuse comes to light but is often downplayed because it is based on hearsay and so on. Occasionally enough of the post mortem information would get out so impartial parties can draw some conclusions.

An example. A well known German bodybuilder dies after collapsing and being rushed to hospital. Believe it or not, Clenbuterol is blamed. Clenbuterol had been around for many year in bodybuilding but was relatively new on the athletic scene. No mention of steroids are made, even if any idiot knows that he has been using copious amounts for over 15 years. The facts comes to light later after a private analysis if the circumstances. The bodybuilder suffered for a stomach ulcer that stared bleeding. The bleeding could not be stopped and this was the cause of death. We know that he was using steroids in large amounts, we know that steroids increase the blood clotting time and so you can logically conclude what happened. Did steroids kill him - indirectly yes, but no mention was made of it.

Similarly we know that increased levels of testosterone can cause prostate enlargement there seems to be a correlation with prostate cancer. The problem is that you cannot conclusively link the tow, not by a long shot. For every guy IO know that has developed prostate problem while taking steroids or GH, there are 1000 guys that had no problems whatsoever. The incidences of cancer evokes the same kind of ratios.
Over the years one conclusion I have drawn seem to make the most sense. Steroids do not cause many of the conditions they get blamed for, but they rater aggravate an existing condition the user was unaware of.

Consider some of the myths doctors spread regarding steroids, hair loss for instance. Steroids do not cause hair loss, but can accelerate male pattern balding. This means that if you are going to lose your hair naturally, steroids will accelerate the process. This far different from saying that steroids makes everybody lose their hair.

Can GH and IGF-1 be correlated to cancer and other conditions? Logically one has to say yes based on the same information we get from tracking the long term human use, a study rejected by the medical field that seem to rather trust one or two obscure animal study and then has no problem prescribing medication to innocent people.

I believe the risks are the same as anything and the risks are aggravated by preexisting conditions as well as other drug use or unhealthy habits.